Publication: Moving beyond unsolicited consultation: additional impact of a structured intervention on mortality in Staphylococcus aureus bacteraemia.
dc.contributor.author | Perez-Rodriguez, Maria Teresa | |
dc.contributor.author | Sousa, Adrian | |
dc.contributor.author | Lopez-Cortes, Luis Eduardo | |
dc.contributor.author | Martinez-Lamas, Lucia | |
dc.contributor.author | Val, Nuria | |
dc.contributor.author | Baroja, Aida | |
dc.contributor.author | Nodar, Andres | |
dc.contributor.author | Vasallo, Francisco | |
dc.contributor.author | Alvarez-Fernandez, Maximiliano | |
dc.contributor.author | Crespo, Manuel | |
dc.contributor.author | Rodriguez-Baño, Jesus | |
dc.date.accessioned | 2023-01-25T10:29:09Z | |
dc.date.available | 2023-01-25T10:29:09Z | |
dc.date.issued | 2019 | |
dc.description.abstract | Some evidence-based bundles have tried to standardize the management of Staphylococcus aureus bacteraemia (SAB) to improve the outcome. The aim of our study was to analyse the additional impact on mortality of a structured intervention in patients with SAB. Compliance with the bundle was evaluated in an ambispective cohort of patients with SAB, which included a retrospective cohort [including patients treated before and after the implementation of a bacteraemia programme (no-BP and BP, respectively)] and a prospective cohort (i-BP), in which an additional specific intervention for bundle application was implemented. Multivariate logistic regression was used to measure the influence of the independent variables including compliance with the bundle on 14 and 30 day crude mortality. A total of 271 adult patients with SAB were included. Mortality was significantly different among the three groups (no-BP, BP and i-BP): mortality at 14 days was 18% versus 7% versus 2%, respectively, P = 0.002; and mortality at 30 days was 20% versus 12% versus 5%, respectively, P = 0.011. The factors associated with 14 and 30 day mortality in multivariable analysis were heart failure (OR = 7.63 and OR = 2.27, respectively), MRSA infection (OR = 4.02 and OR = 4.37, respectively) and persistent bacteraemia (OR = 11.01 and OR = 7.83, respectively); protective factors were catheter-related bacteraemia (OR = 0.16 and OR = 0.19, respectively) and >75% bundle compliance (OR = 0.15 and OR = 0.199, respectively). Time required to perform the intervention and the follow-up was 50 min (IQR 40-55 min) per patient. High-level compliance with a standardized bundle of intervention for management of SAB that requires little time was associated with lower mortality at 14 and 30 days. | |
dc.description.version | Si | |
dc.identifier.citation | Pérez-Rodríguez MT, Sousa A, López-Cortés LE, Martínez-Lamas L, Val N, Baroja A, et al. Moving beyond unsolicited consultation: additional impact of a structured intervention on mortality in Staphylococcus aureus bacteraemia. J Antimicrob Chemother. 2019 Apr 1;74(4):1101-1107. | |
dc.identifier.doi | 10.1093/jac/dky556 | |
dc.identifier.essn | 1460-2091 | |
dc.identifier.pmid | 30689894 | |
dc.identifier.unpaywallURL | https://academic.oup.com/jac/article-pdf/74/4/1101/28078278/dky556.pdf | |
dc.identifier.uri | http://hdl.handle.net/10668/13473 | |
dc.issue.number | 4 | |
dc.journal.title | The Journal of antimicrobial chemotherapy | |
dc.journal.titleabbreviation | J Antimicrob Chemother | |
dc.language.iso | en | |
dc.organization | Instituto de Biomedicina de Sevilla-IBIS | |
dc.organization | Hospital Universitario Virgen Macarena | |
dc.page.number | 1101-1107 | |
dc.provenance | Realizada la curación de contenido 17/06/2025. | |
dc.publisher | Oxford University Press | |
dc.pubmedtype | Journal Article | |
dc.pubmedtype | Research Support, Non-U.S. Gov't | |
dc.relation.publisherversion | https://academic.oup.com/jac/article-lookup/doi/10.1093/jac/dky556 | |
dc.rights.accessRights | Restricted Access | |
dc.subject | Bacteremia | |
dc.subject | Evidence-Based Practice | |
dc.subject | Health Impact Assessment | |
dc.subject | Odds Ratio | |
dc.subject | Staphylococcal Infections | |
dc.subject.decs | Mortalidad | |
dc.subject.decs | Pacientes | |
dc.subject.decs | Catéteres | |
dc.subject.decs | Staphylococcus aureus resistente a Meticilina | |
dc.subject.decs | Insuficiencia cardíaca | |
dc.subject.decs | Infecciones | |
dc.subject.mesh | Adult | |
dc.subject.mesh | Aged | |
dc.subject.mesh | Aged, 80 and over | |
dc.subject.mesh | Disease Management | |
dc.subject.mesh | Female | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Male | |
dc.subject.mesh | Methicillin-Resistant Staphylococcus aureus | |
dc.subject.mesh | Middle Aged | |
dc.subject.mesh | Quality Indicators, Health Care | |
dc.subject.mesh | Referral and Consultation | |
dc.subject.mesh | Risk Factors | |
dc.subject.mesh | Staphylococcus aureus | |
dc.title | Moving beyond unsolicited consultation: additional impact of a structured intervention on mortality in Staphylococcus aureus bacteraemia. | |
dc.type | research article | |
dc.type.hasVersion | VoR | |
dc.volume.number | 74 | |
dspace.entity.type | Publication |
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