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Demographic, lifestyle, and other factors in relation to antimüllerian hormone levels in mostly late premenopausal women.

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Date

2017

Authors

Jung, Seungyoun
Allen, Naomi
Arslan, Alan A
Baglietto, Laura
Brinton, Louise A
Egleston, Brian L
Falk, Roni
Fortner, Renée T
Helzlsouer, Kathy J
Idahl, Annika

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Abstract

To identify reproductive, lifestyle, hormonal, and other correlates of circulating antimüllerian hormone (AMH) concentrations in mostly late premenopausal women. Cross-sectional study. Not applicable. A total of 671 premenopausal women not known to have cancer. None. Concentrations of AMH were measured in a single laboratory using the picoAMH ELISA. Multivariable-adjusted median (and interquartile range) AMH concentrations were calculated using quantile regression for several potential correlates. Older women had significantly lower AMH concentrations (≥40 [n = 444] vs. Among premenopausal women, lower AMH concentrations are associated with older age, a younger age at menarche, and currently using oral contraceptives, suggesting these factors are related to a lower number or decreased secretory activity of ovarian follicles.

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Adult
Age Factors
Anti-Mullerian Hormone
Asia
Biomarkers
Contraceptives, Oral, Hormonal
Cross-Sectional Studies
Enzyme-Linked Immunosorbent Assay
Europe
Female
Humans
Life Style
Middle Aged
Multivariate Analysis
Ovarian Reserve
Premenopause
Prospective Studies
Sex Hormone-Binding Globulin
Testosterone Congeners
United States
Young Adult

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Keywords

Antimüllerian hormone, demographic, lifestyle, ovarian reserve, reproductive factors

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