Activity of Fosfomycin on Clinical Isolates of Campylobacter jejuni and Campylobacter coli of Enteric Origin.

Abstract

We read with interest the report by Aguilar-Company et al. (1) on two cases of recurrent enteritis due to Campylobacter coli successfully treated with oral fosfomycin-tromethamine. Campylobacter spp. are among the main microorganisms responsible for enteritis and are the principal cause of bacterial diarrhea in our setting, ahead of the genus Salmonella; they are responsible for 44.0% of cases, a percentage that has substantially increased over recent years (2). Although the disease is often mild and self-limiting, it is frequently observed in patients with immunologic alterations and there is growing resistance to macrolides and fluoroquinolones, increasing the risk of a lethal outcome (3).