Publication: Influence of renal function on anticoagulation control in patients with non-valvular atrial fibrillation taking vitamin K antagonists
No Thumbnail Available
Identifiers
Date
2017-09-01
Authors
Lobos-Bejarano, Jose M.
Castellanos Rodriguez, Angel
Barrios, Vivencio
Escobar, Carlos
Polo-Garcia, Jose
Carlos del Castillo-Rodriguez, Jose
Vargas-Ortega, Diego
Lopez-Pineda, Adriana
Prieto-Valiente, Luis
Lip, Gregory Y. H.
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Wiley-hindawi
Metrics
Export
Abstract
Background and PurposeChronic kidney disease (CKD) has been related to poor anticoagulation control and an increased risk of bleeding. This study aims to evaluate the association between impaired renal function (eGFR 2 points) showed no significant predictive capacity for TTR (AUC 0.528, P=.354). The average TTR was similar for both sexes (P=.255), but with a higher percentage of males subjects with TTR 65% (P=.013).ConclusionChronic kidney disease is associated with poor anticoagulation control in patients with non-valvular AF taking VKA. The SAMe-TT2R2 score was not predictive of poor TTR in the subgroup with CKD, although a modest predictive value for poor TTR was found in those without CKD.
Description
MeSH Terms
DeCS Terms
CIE Terms
Keywords
anticoagulation, atrial fibrillation, chronic kidney disease, vitamin K antagonist, Chronic kidney-disease, Same-tt2r2 score, Stroke, Quality, Warfarin, Risk, Mortality, Spain, Care, Inr