Publication: Cervical determinants of anal HPV infection and high-grade anal lesions in women: a collaborative pooled analysis.
dc.contributor.author | Lin, Chunqing | |
dc.contributor.author | Slama, Jiri | |
dc.contributor.author | Gonzalez, Paula | |
dc.contributor.author | Goodman, Marc T | |
dc.contributor.author | Xia, Ningshao | |
dc.contributor.author | Kreimer, Aimée R | |
dc.contributor.author | Wu, Ting | |
dc.contributor.author | Hessol, Nancy A | |
dc.contributor.author | Shvetsov, Yurii | |
dc.contributor.author | Ortiz, Ana P | |
dc.contributor.author | Grinsztejn, Beatriz | |
dc.contributor.author | Moscicki, Anna-Barbara | |
dc.contributor.author | Heard, Isabelle | |
dc.contributor.author | Del Refugio González Losa, María | |
dc.contributor.author | Kojic, Erna M | |
dc.contributor.author | Schim van der Loeff, Maarten F | |
dc.contributor.author | Wei, Feixue | |
dc.contributor.author | Longatto-Filho, Adhemar | |
dc.contributor.author | Mbulawa, Zizipho A | |
dc.contributor.author | Palefsky, Joel M | |
dc.contributor.author | Sohn, Annette H | |
dc.contributor.author | Hernandez, Brenda Y | |
dc.contributor.author | Robison, Katina | |
dc.contributor.author | Simpson, Steve | |
dc.contributor.author | Conley, Lois J | |
dc.contributor.author | de Pokomandy, Alexandra | |
dc.contributor.author | van der Sande, Marianne A B | |
dc.contributor.author | Dube Mandishora, Racheal S | |
dc.contributor.author | Volpini, Lays P B | |
dc.contributor.author | Pierangeli, Alessandra | |
dc.contributor.author | Romero, Byron | |
dc.contributor.author | Wilkin, Timothy | |
dc.contributor.author | Franceschi, Silvia | |
dc.contributor.author | Hidalgo-Tenorio, Carmen | |
dc.contributor.author | Ramautarsing, Reshmie A | |
dc.contributor.author | Park, Ina U | |
dc.contributor.author | Tso, Fernanda K | |
dc.contributor.author | Godbole, Sheela | |
dc.contributor.author | D'Hauwers, Kathleen W M | |
dc.contributor.author | Sehnal, Borek | |
dc.contributor.author | Menezes, Lynette J | |
dc.contributor.author | Heráclio, Sandra A | |
dc.contributor.author | Clifford, Gary M | |
dc.date.accessioned | 2023-01-25T13:35:04Z | |
dc.date.available | 2023-01-25T13:35:04Z | |
dc.date.issued | 2019-06-13 | |
dc.description.abstract | Cervical cancer screening might contribute to the prevention of anal cancer in women. We aimed to investigate if routine cervical cancer screening results-namely high-risk human papillomavirus (HPV) infection and cytohistopathology-predict anal HPV16 infection, anal high-grade squamous intraepithelial lesions (HSIL) and, hence, anal cancer. We did a systematic review of MEDLINE, Embase, and the Cochrane library for studies of cervical determinants of anal HPV and HSIL published up to Aug 31, 2018. We centrally reanalysed individual-level data from 13 427 women with paired cervical and anal samples from 36 studies. We compared anal high-risk HPV prevalence by HIV status, cervical high-risk HPV, cervical cytohistopathology, age, and their combinations, using prevalence ratios (PR) and 95% CIs. Among 3255 women with anal cytohistopathology results, PRs were similarly calculated for all anal HSIL and HPV16-positive anal HSIL. Cervical and anal HPV infections were highly correlated. In HIV-negative women, anal HPV16 prevalence was 41% (447/1097) in cervical HPV16-positive versus 2% (214/8663) in cervical HPV16-negative women (PR 16·5, 95% CI 14·2-19·2, p HPV-based cervical cancer screening programmes might help to stratify anal cancer risk, irrespective of HIV status. For targeted secondary anal cancer prevention in high-risk groups, HIV-negative women with cervical HPV16, especially those older than 45 years, have a similar anal cancer risk profile to that of HIV-positive women. International Agency for Research on Cancer. | |
dc.identifier.doi | 10.1016/S1473-3099(19)30164-1 | |
dc.identifier.essn | 1474-4457 | |
dc.identifier.pmc | PMC6656696 | |
dc.identifier.pmid | 31204304 | |
dc.identifier.pubmedURL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656696/pdf | |
dc.identifier.unpaywallURL | http://www.thelancet.com/article/S1473309919301641/pdf | |
dc.identifier.uri | http://hdl.handle.net/10668/14122 | |
dc.issue.number | 8 | |
dc.journal.title | The Lancet. Infectious diseases | |
dc.journal.titleabbreviation | Lancet Infect Dis | |
dc.language.iso | en | |
dc.organization | Hospital Universitario Virgen de las Nieves | |
dc.page.number | 880-891 | |
dc.pubmedtype | Journal Article | |
dc.pubmedtype | Research Support, N.I.H., Extramural | |
dc.pubmedtype | Research Support, Non-U.S. Gov't | |
dc.pubmedtype | Systematic Review | |
dc.rights.accessRights | open access | |
dc.subject.mesh | Anus Neoplasms | |
dc.subject.mesh | Early Detection of Cancer | |
dc.subject.mesh | Female | |
dc.subject.mesh | Global Health | |
dc.subject.mesh | HIV Seropositivity | |
dc.subject.mesh | Human papillomavirus 16 | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Papillomavirus Infections | |
dc.subject.mesh | Prevalence | |
dc.subject.mesh | Uterine Cervical Neoplasms | |
dc.title | Cervical determinants of anal HPV infection and high-grade anal lesions in women: a collaborative pooled analysis. | |
dc.type | research article | |
dc.type.hasVersion | VoR | |
dc.volume.number | 19 | |
dspace.entity.type | Publication |