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Data set on a study of gene expression in peripheral samples to identify biomarkers of severity of allergic and nonallergic asthma

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Date

2017-02

Authors

Baos, Selene
Calzada, David
Cremades, Lucía
Sastre, Joaquín
Quiralte, Joaquín
Florido, Fernando
Lahoz, Carlos
Cárdaba, Blanca

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Elsevier
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Abstract

This article contains information related to the research article entitled "Biomarkers associated with disease severity in allergic and nonallergic asthma" (S. Baos, D. Calzada, L. Cremades, J. Sastre, J. Quiralte, F. Florido, C. Lahoz, B. Cárdaba, In press). Specifically, the clinical criteria stablished for selecting the study population (n=104 subjects) are described. Moreover, this article describes the criteria for selecting the 94 genes to be analyzed in PBMCs (peripheral blood mononuclear cells), it is provided a description of these genes and a Table with the genes most differentially expressed by clinical phenotypes and, finally it is detailed the experimental methodology followed for studying the protein expression of MSR1 (macrophage scavenger receptor 1), one of the genes evaluated in the research.

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Medical Subject Headings::Diseases::Respiratory Tract Diseases::Bronchial Diseases::Asthma
Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers
Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear
Medical Subject Headings::Anatomy::Hemic and Immune Systems::Immune System::Mononuclear Phagocyte System
Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype
Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biochemistry::Proteomics
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Scavenger

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Keywords

Asthma, Allergy, Biomarkers, Gene expression, Peripheral samples, Asma, Biomarcadores, Leucocitos mononucleares, Sistema mononuclear fagocítico, Proteómica, Receptores depuradores

Citation

Baos S, Calzada D, Cremades L, Sastre J, Quiralte J, Florido F. Data set on a study of gene expression in peripheral samples to identify biomarkers of severity of allergic and nonallergic asthma. Data Brief. 2017; 10:505-510