Publication:
Toscana virus in Spain

dc.contributor.authorSanbonmatsu-Gámez, Sara
dc.contributor.authorPérez-Ruiz, Mercedes
dc.contributor.authorCollao, Ximena
dc.contributor.authorSánchez-Seco, María Paz
dc.contributor.authorMorillas-Márquez, Francisco
dc.contributor.authorRosa-Fraile, Manuel de la
dc.contributor.authorNavarro-Marí, José María
dc.contributor.authorTenorio, Antonio
dc.contributor.authoraffiliation[Sanbonmatsu-Gámez,S; Pérez-Ruiz,M; Rosa-Fraile, M de la; Navarro-Marí,JM] Hospital Universitario Virgen de las Nieves, Granada, Spain. [Collao,X; Sánchez-Seco,MP; Tenorio,A] Instituto de Salud Carlos III, Madrid, Spain. [Morillas-Márquez,F] Universidad de Granada, Granada, Spain.es
dc.contributor.funderGrant sponsor was Red EVITAR, Fondo de Investigaciones Sanitarias, Spanish Ministry of Health, grant no. G03/059. Ximena Collao has a research grant from Valparaiso University (MECESUP project, Chile). The study of vectors, i.e., capture of phlebotomines and taxonomic classification, was supported by the Junta de Andalucía, research grant CVI 176.
dc.date.accessioned2012-11-08T13:16:24Z
dc.date.available2012-11-08T13:16:24Z
dc.date.issued2005-11
dc.descriptionJournal Article; Research Support, Non-U.S. Gov't;es
dc.description.abstractToscana virus (TOSV, Phlebovirus, family Bunyaviridae) infection is one of the most prevalent arboviruses in Spain. Within the objectives of a multidisciplinary network, a study on the epidemiology of TOSV was conducted in Granada, in southern Spain. The overall seroprevalence rate was 24.9%, significantly increasing with age. TOSV was detected in 3 of 103 sandfly pools by viral culture or reverse transcription-polymerase chain reaction from a region of the L gene. Nucleotide sequence homology was 99%-100% in TOSV from vectors and patients and 80%-81% compared to the Italian strain ISS Phl.3. Sequencing of the N gene of TOSV isolates from patients and vectors indicated 87%-88% and 100% homology at the nucleotide and amino acid levels, respectively, compared to the Italian strain. These findings demonstrate the circulation of at least 2 different lineages of TOSV in the Mediterranean basin, the Italian lineage and the Spanish lineage.es
dc.description.versionYeses
dc.identifier.citationSanbonmatsu-Gámez S, Pérez-Ruiz M, Collao X, Sánchez-Seco MP, Morillas-Márquez F, Rosa-Fraile M de la, et al. Toscana virus in Spain.Emerg Infect Dis. 2005 Nov;11(11):1701-7.es
dc.identifier.doi10.3201/eid1111.080851
dc.identifier.essn1080-6059
dc.identifier.issn1080-6040
dc.identifier.pmcPMC3367369
dc.identifier.pmid16318721
dc.identifier.urihttp://hdl.handle.net/10668/608
dc.journal.titleEmerging infectious diseases
dc.language.isoen
dc.publisherU.S. National Center for Infectious Diseaseses
dc.relation.publisherversionhttp://wwwnc.cdc.gov/eid/article/11/11/05-0851_article.htmes
dc.rights.accessRightsopen access
dc.subjectAnimaleses
dc.subjectAnticuerpos Antiviraleses
dc.subjectFemeninoes
dc.subjectHumanoses
dc.subjectInmunoglobulina Ges
dc.subjectInsectos Vectoreses
dc.subjectMasculinoes
dc.subjectPhlebotomuses
dc.subjectFiebre por Flebótomoses
dc.subjectFilogeniaes
dc.subjectPrevalenciaes
dc.subjectVirus de Nápoles de la Fiebre de la Mosca de los Arenaleses
dc.subjectAnálisis de Secuencia de ADNes
dc.subjectEspañaes
dc.subjectProteínas Viraleses
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies, Virales
dc.subject.meshMedical Subject Headings::Check Tags::Femalees
dc.subject.meshMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humanses
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Immunoglobulin Isotypes::Immunoglobulin Ges
dc.subject.meshMedical Subject Headings::Health Care::Environment and Public Health::Public Health::Disease Transmission, Infectious::Disease Vectors::Arthropod Vectors::Insect Vectorses
dc.subject.meshMedical Subject Headings::Check Tags::Malees
dc.subject.meshMedical Subject Headings::Organisms::Eukaryota::Animals::Invertebrates::Arthropods::Insects::Diptera::Psychodidae::Phlebotomuses
dc.subject.meshMedical Subject Headings::Diseases::Virus Diseases::Arbovirus Infections::Phlebotomus Feveres
dc.subject.meshMedical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phylogenyes
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalencees
dc.subject.meshMedical Subject Headings::Organisms::Viruses::RNA Viruses::Bunyaviridae::Phlebovirus::Sandfly fever Naples viruses
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Sequence Analysis::Sequence Analysis, DNAes
dc.subject.meshMedical Subject Headings::Geographicals::Geographic Locations::Europe::Spaines
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Viral Proteinses
dc.titleToscana virus in Spaines
dc.typeresearch article
dc.type.hasVersionVoR
dspace.entity.typePublication

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