Publication: Comments on: Differential IgG4-Producing Plasma Cell Infiltration in Non- and Post-Transplant Plasma Cell Hepatitis.
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Date
2022-08-05
Authors
Aguilera, Isabel
Sousa, Jose Manuel
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Volume Title
Publisher
Frontiers Media SA
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Abstract
We read with interest the article by Horwich et al. about IgG4-producing plasma cells. The aim of the study was to use IgG4-positivity as a differential biomarker for distinct clinical presentations of plasma cell hepatitis before and after liver transplantation. They found a high degree of IgG4-PC infiltration more frequently associated with plasma cell rejection (PCR) than other types of AIH and concluded that IgG4-positivity might serve as a valuable diagnostic tool in the post-LT setting.
Description
MeSH Terms
Hepatitis
Humans
Immunoglobulin G
Inflammation
Liver Transplantation
Plasma Cells
Transplants
Humans
Immunoglobulin G
Inflammation
Liver Transplantation
Plasma Cells
Transplants
DeCS Terms
Inmunoglobulina G
Células plasmáticas
Inseminación artificial homóloga
Trasplante de hígado
Biomarcadores
Hepatitis
Reacción en cadena de la polimerasa
Células plasmáticas
Inseminación artificial homóloga
Trasplante de hígado
Biomarcadores
Hepatitis
Reacción en cadena de la polimerasa
CIE Terms
Keywords
GSTT1, IgG4, PC-rich R, liver transplant, plasma cells
Citation
Aguilera I, Sousa JM. Comments on: Differential IgG4-Producing Plasma Cell Infiltration in Non- and Post-Transplant Plasma Cell Hepatitis. Transpl Int. 2022 Aug 5;35:10590.