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A novel human tumoroid 3D model of sustained ACTH-secreting cell cultures to study critically needed therapies for Cushing's disease

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dc.contributor.authorFuentes-Fayos, Antonio C.
dc.contributor.authorLuque, Raúl M.
dc.contributor.authoraffiliation[Fuentes-Fayos,AC; Luque,RM] Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Cordoba, Spain. [Fuentes-Fayos,AC; Luque,RM] Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain. [Fuentes-Fayos,AC; Luque,RM] Reina Sofia University Hospital (HURS), Cordoba, Spain. CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Cordoba, Spain.
dc.contributor.funderThis work has been supported by the Spanish Ministry of Science, Innovation and Universities (Grant PID2019-105564RB-I00; Predoctoral contract FPU16-05059), Junta de Andalucía (BIO-0139) and CIBERobn
dc.date.accessioned2022-11-23T13:54:48Z
dc.date.available2022-11-23T13:54:48Z
dc.date.issued2021-05-13
dc.description.versionYeses_ES
dc.identifier.citationFuentes-Fayos AC, Luque RM. A novel human tumoroid 3D model of sustained ACTH-secreting cell cultures to study critically needed therapies for Cushing's disease. EBioMedicine. 2021 May;67:103368es_ES
dc.identifier.doi10.1016/j.ebiom.2021.103368es_ES
dc.identifier.essn2352-3964
dc.identifier.pmcPMC8206815
dc.identifier.pmid33993049es_ES
dc.identifier.urihttp://hdl.handle.net/10668/4401
dc.journal.titleEBioMedicine
dc.language.isoen
dc.page.number2 p.
dc.publisherElsevier B.V.es_ES
dc.relation.publisherversionhttps://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00161-4/fulltextes_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectCorticotrophes_ES
dc.subjectPituitary glandes_ES
dc.subjectPituitary neoplasmses_ES
dc.subjectAdrenocorticotropic hormonees_ES
dc.subjectCushing's diseasees_ES
dc.subjectCorticotrofoses_ES
dc.subjectHipófisises_ES
dc.subjectNeoplasias hipofisariases_ES
dc.subjectHormona adrenocorticotrópicaes_ES
dc.subjectHipersecreción de la hormona adrenocorticotrópica pituitaria (HACT)es_ES
dc.subjectEnfermedad de Cushinges_ES
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pituitary Hormones::Pituitary Hormones, Anterior::Pro-Opiomelanocortin::Adrenocorticotropic Hormonees_ES
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Cell Culture Techniqueses_ES
dc.subject.meshMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humanses_ES
dc.subject.meshMedical Subject Headings::Diseases::Endocrine System Diseases::Pituitary Diseases::Hyperpituitarism::Pituitary ACTH Hypersecretiones_ES
dc.subject.meshMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Micees_ES
dc.subject.meshMedical Subject Headings::Organisms::Eukaryota::Animalses_ES
dc.subject.meshMedical Subject Headings::Anatomy::Cells::Endocrine Cells::Corticotrophses_ES
dc.subject.meshMedical Subject Headings::Diseases::Endocrine System Diseases::Pituitary Diseases::Pituitary Neoplasmses_ES
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pituitary Hormones::Pituitary Hormones, Anterior::Pro-Opiomelanocortines_ES
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Cell Culture Techniques::Primary Cell Culturees_ES
dc.subject.meshMedical Subject Headings::Health Care::Health Care Facilities, Manpower, and Services::Health Facilities::Laboratorieses_ES
dc.subject.meshMedical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Linees_ES
dc.subject.meshMedical Subject Headings::Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproductiones_ES
dc.subject.meshMedical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Homeostasises_ES
dc.titleA novel human tumoroid 3D model of sustained ACTH-secreting cell cultures to study critically needed therapies for Cushing's diseasees_ES
dc.typeletter
dc.type.hasVersionVoR
dspace.entity.typePublication

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