Publication:
Resistance to thyroid hormone and down syndrome: coincidental association or genetic linkage?

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Abstract
We report the first case of RTH and DS. Although this congruence could be coincidental, we cannot exclude a possible linkage between both syndromes.
Description
Carta al Director
MeSH Terms
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Diseases::Nervous System Diseases::Neurologic Manifestations::Neurobehavioral Manifestations::Intellectual Disability::Down Syndrome
Medical Subject Headings::Diseases::Endocrine System Diseases::Thyroid Diseases::Hyperthyroxinemia::Thyroid Hormone Resistance Syndrome
Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Thyroid Hormones::Thyronines::Triiodothyronine
Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Globulins::Thyroglobulin
Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Peroxidases::Iodide Peroxidase
Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pituitary Hormones::Pituitary Hormones, Anterior
Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Neurobehavioral Manifestations::Psychomotor Disorders
Medical Subject Headings::Anatomy::Cells::Cellular Structures::Chromosomes::Chromosomes, Mammalian::Chromosomes, Human::Chromosomes, Human, 21-22 and Y
Medical Subject Headings::Anatomy::Cells::Cellular Structures::Chromosomes::Chromosomes, Mammalian::Chromosomes, Human::Chromosomes, Human, 1-3::Chromosomes, Human, Pair 3
Medical Subject Headings::Named Groups::Persons::Age Groups::Child::Child, Preschool
Medical Subject Headings::Check Tags::Male
DeCS Terms
CIE Terms
Keywords
Síndrome de Down, Síndrome de Resistencia a Hormonas Tiroideas, Triyodotironina, Tiroglobulina, Yoduro Peroxidasa, Tirotropina, Trastornos Psicomotores, Cromosomas Humanos Par 21, Cromosomas Humanos Par 3, Resistance to thyroid hormone, Down syndrome, TRβ gene, goiter, genetic linkage
Citation
Fernández-García JC, López-Medina JA, Berchid-Debdi M, Tinahones Madueño FJ. Resistance to thyroid hormone and down syndrome: coincidental association or genetic linkage? Thyroid. 2012; 22(9):973-974