Publication: Recommendations of the Spanish Antibiogram Committee (COESANT) for selecting antimicrobial agents and concentrations for in vitro susceptibility studies using automated systems.
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Identifiers
Date
2019-01-06
Authors
Canton, Rafael
Oliver, Antonio
Alos, Juan Ignacio
de Benito, Natividad
Bou, German
Campos, Jose
Calvo, Jorge
Canut, Andres
Castillo, Javier
Cercenado, Emilia
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Automated antimicrobial susceptibility testing devices are widely implemented in clinical microbiology laboratories in Spain, mainly using EUCAST (European Committee on Antimicrobial Susceptibility Testing) breakpoints. In 2007, a group of experts published recommendations for including antimicrobial agents and selecting concentrations in these systems. Under the patronage of the Spanish Antibiogram Committee (Comité Español del Antibiograma, COESANT) and the Study Group on Mechanisms of Action and Resistance to Antimicrobial Agents (GEMARA) from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), and aligned with the Spanish National Plan against Antimicrobial Resistance (PRAN), a group of experts have updated this document. The main modifications from the previous version comprise the inclusion of new antimicrobial agents, adaptation of the ranges of concentrations to cover the EUCAST breakpoints and epidemiological cut-off values (ECOFFs), and the inference of new resistance mechanisms. This proposal should be considered by different manufacturers and users when designing new panels or cards. In addition, recommendations for selective reporting are also included. With this approach, the implementation of EUCAST breakpoints will be easier, increasing the quality of antimicrobial susceptibility testing data and their microbiological interpretation. It will also benefit epidemiological surveillance studies as well as the clinical use of antimicrobials aligned with antimicrobial stewardship programs.
Description
MeSH Terms
Anti-Infective Agents
Automation, Laboratory
Microbial Sensitivity Tests
Spain
Automation, Laboratory
Microbial Sensitivity Tests
Spain
DeCS Terms
Antiinfecciosos
Automatizacion de laboratorios
España
Pruebas de sensibilidad microbiana
Automatizacion de laboratorios
España
Pruebas de sensibilidad microbiana
CIE Terms
Keywords
Antibiogram, Antibiograma, Automated susceptibility testing systems, CMI, Concentraciones mínimas antimicrobianas, MICs, Minimum antimicrobial concentrations, Sistemas automáticos de detección de sensibilidad, Antibiograma, Sistemas automaticos de deteccion de sensibilidad, Concentraciones minimas antimicrobianas, CMI
Citation
Cantón R, Oliver A, Alós JI, de Benito N, Bou G, Campos J, et al. Recommendations of the Spanish Antibiogram Committee (COESANT) for selecting antimicrobial agents and concentrations for in vitro susceptibility studies using automated systems. Enferm Infecc Microbiol Clin (Engl Ed). 2020 Apr;38(4):182-187.