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Role of Age and Sex in the Diagnosis of Early-stage Malignant Melanoma: A Cross-Sectional study.

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dc.contributor.authorMoreno-Ramírez, David
dc.contributor.authorOjeda-Vila, Teresa
dc.contributor.authorRíos-Martín, Juan J
dc.contributor.authorNieto-García, Adoración
dc.contributor.authorFerrándiz, Lara
dc.contributor.authoraffiliation[Moreno-Ramírez,D; Ojeda-Vila,T; Ferrándiz,L] Dermatology Unit, Hospital Universitario Virgen Macarena, Sevilla, Spain. [Ríos-Martín,JJ] Pathology Unit, Hospital Universitario Virgen Macarena, Sevilla, Spain. [Nieto-García,A] Public Health and Epidemiology Department, Medical School, Universidad de Sevilla, Seville, Spain.es
dc.contributor.funderThe Trends in the Diagnosis of Melanoma(TEDIMEL) Project Study Group is funded by a competitive public grant of the Health Institute Carlos III of the Spanish Health Ministry (IP 10-1929 2010-2013).
dc.date.accessioned2016-03-04T11:59:20Z
dc.date.available2016-03-04T11:59:20Z
dc.date.issued2015-11-04
dc.descriptionJournal Article;es
dc.description.abstractAge and sex have been identified as predictors of outcome in malignant melanoma (MM). This aim of this multicentre, cross-sectional study was to analyse the role of age and sex as explanatory variables for the diagnosis of thin MM. A total of 2430 patients with MM were recruited. Cases of in situ-T1 MM were more frequent than T2-T4 MM (56.26% vs. 43.74%). Breslow thickness increased throughout decades of life (analysis of variance (ANOVA) p < 0.001), with a weak correlation between Breslow thickness and patient's age (r   = 0.202, p < 0.001). Breslow thickness was significantly less in women (1.79 vs. 2.38 mm, p = 0.0001). Binary logistic regression showed a significant (p < 0.001) odds ratio for age 0-29 years (1.18), and 30-59 years (1.16), and for women (1.09). Age and sex explained 3.64% of the variation observed in Tis-T1 frequency (R2 = 0.0364). Age and sex appear to explain a low percentage of the variation in the early detection of MM.es
dc.description.versionYeses
dc.identifier.citationMoreno-Ramírez D, Ojeda-Vila T, Ríos-Martín JJ, Nieto-García A, Ferrándiz L. Role of Age and Sex in the Diagnosis of Early-stage Malignant Melanoma: A Cross-Sectional study. Acta Derm. Venereol. 2015; 95(8):940-2es
dc.identifier.doi10.2340/00015555-2115
dc.identifier.essn1651-2057
dc.identifier.issn0001-5555
dc.identifier.pmid25881630
dc.identifier.urihttp://hdl.handle.net/10668/2152
dc.journal.titleActa dermato-venereologica
dc.language.isoen
dc.publisherSociety for the Publication of Acta Dermato-Venereologicaes
dc.relation.publisherversionhttp://www.medicaljournals.se/acta/content/?doi=10.2340/00015555-2115es
dc.rights.accessRightsopen access
dc.subjectMalignant melanomaes
dc.subjectPrognostic predictorses
dc.subjectThin melanomaes
dc.subjectEarly-stage malignant melanomaes
dc.subjectAgees
dc.subjectSexes
dc.subjectEstudios transversaleses
dc.subjectModelos logísticoses
dc.subjectMelanomaes
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Analysis of Variancees
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studieses
dc.subject.meshMedical Subject Headings::Check Tags::Femalees
dc.subject.meshMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humanses
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models, Statistical::Logistic Modelses
dc.subject.meshMedical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Germ Cell and Embryonal::Neuroectodermal Tumors::Neuroendocrine Tumors::Melanomaes
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Odds Ratioes
dc.titleRole of Age and Sex in the Diagnosis of Early-stage Malignant Melanoma: A Cross-Sectional study.es
dc.typeresearch article
dc.type.hasVersionVoR
dspace.entity.typePublication

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