The Value of Transcranial Doppler Sonography in Hyperperfusion Syndrome after Carotid Artery Stenting: A Nationwide Prospective Study.

Abstract

Cerebral hyperperfusion syndrome (CHS) is a life-threatening complication, defined as a combination of clinical features with evidence of hyperperfusion >100% [1]. Hyperperfusion has been reported in 1% to 3% after carotid artery stenting (CAS) [1]. Although hyperperfusion evidence in those patients with the typical clinical syndrome seems to be a critical aspect of the CHS, the severity of the cerebral perfusion increase that is needed to develop the CHS is not clear [2]. Definitions with different degrees of hyperperfusion have been used to diagnose CHS, although the most widely used is an increase in cerebral blood flow of more than 100% compared with baseline values [1]. The aim of the study was to validate prospectively the transcranial Doppler (TCD) criteria in diagnosis of CHS after CAS in a nationwide study.