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Low levels of morning salivary alpha-amylase activity predict higher number of depressive symptoms in a community sample of children

dc.contributor.authorFrancisco Maldonado, Enrique
dc.contributor.authorFernandez, Eugenia
dc.contributor.authorVictoria Trianes, Maria
dc.contributor.authorOrtiz, Carmen
dc.contributor.authorEnguix, Alfredo
dc.contributor.authorNislin, Mari
dc.contributor.authoraffiliation[Francisco Maldonado, Enrique] Univ Malaga, Malaga, Spain
dc.contributor.authoraffiliation[Fernandez, Eugenia] Univ Malaga, Malaga, Spain
dc.contributor.authoraffiliation[Victoria Trianes, Maria] Univ Malaga, Malaga, Spain
dc.contributor.authoraffiliation[Ortiz, Carmen] Virgen de la Victoria Hosp, Malaga, Spain
dc.contributor.authoraffiliation[Enguix, Alfredo] Virgen de la Victoria Hosp, Malaga, Spain
dc.contributor.authoraffiliation[Nislin, Mari] Educ Univ Hong Kong, Hong Kong, Hong Kong, Peoples R China
dc.date.accessioned2023-02-12T02:23:38Z
dc.date.available2023-02-12T02:23:38Z
dc.date.issued2018-05-01
dc.description.abstractModels of the etiology of depressive disorders suggest that the onset of a depressive episode is the result of a complex phenomenon based on the interaction between genetic background, critical environmental factors such as life stressors and traumatic events, and the effects of neuroendocrine changes associated with the stress response. Numerous studies have highlighted the usefulness of morning cortisol (C) as a potential predictor of depressive episodes. The aim of this study was to compare the effectiveness of C, salivary alpha-amylase (sAA) activity/output, and the sAA/C ratio in predicting depressive symptoms in a community sample of 99 children aged 8-11 years old. Two saliva samples were obtained in the morning on two different school days. Teachers described their pupils' behavior by using the internalizing problems scales of the Teacher's Report Form (TRF) questionnaire. Our results indicate that, regardless of gender, the best predictor of depressive/withdrawal scores and overall internalizing scores on the TRF was lower mean morning levels of sAA activity. Hence, sAA could be proposed as a biological marker for the risk of developing a first episode of depressive illness in child samples.
dc.identifier.doi10.6018/analesps.34.2.289741
dc.identifier.essn1695-2294
dc.identifier.issn0212-9728
dc.identifier.unpaywallURLhttps://revistas.um.es/analesps/article/download/analesps.34.2.289741/227361
dc.identifier.urihttp://hdl.handle.net/10668/19390
dc.identifier.wosID431109700002
dc.issue.number2
dc.journal.titleAnales de psicologia
dc.journal.titleabbreviationAn. psicol.
dc.language.isoen
dc.organizationHospital Universitario Virgen de la Victoria
dc.page.number224-232
dc.publisherUniv murcia
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectAlpha-Amylase
dc.subjectCortisol
dc.subjectDepressive Symptoms
dc.subjectChildren
dc.subjectObservational Descriptive Study
dc.subjectCortisol awakening response
dc.subjectMajor depression
dc.subjectInternalizing symptoms
dc.subjectImmunoassay system
dc.subjectAdrenal secretion
dc.subjectSex-differences
dc.subjectFollow-up
dc.subjectStress
dc.subjectDisorder
dc.subject16-year-olds
dc.titleLow levels of morning salivary alpha-amylase activity predict higher number of depressive symptoms in a community sample of children
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number34
dc.wostypeArticle
dspace.entity.typePublication
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